The Odyssey should be no problem. I moved from Boston to Baltimore in my 4 cyl VW Passat. I had a Hobie 18 on the trailer, 2 sea kayaks and a mountian bike on the roof rack, and the entire trunck and backseat full. My milage was horrible, but there were no issues. Granted it is a manual transmission, but if this little German car can do it a minivan can.