What we HAVE seen, though, in AC33, AC34 we saw some wrong application of monohull tactics in multihull sailing and we saw some multihull handling mistakes than many of us made when we first started sailing multihulls (but, notably, I don't recall seeing Groupama making any of these types of errors). We've still seen a little bit of this in AC35 but not nearly as much - they are mostly past the inexperience curve.
THIS is my biggest concern when taking monohull sailors and putting them into major multihull regattas (AC, Olympics, etc.). There are VERY, VERY few people who can successfully make this transition.
I won't speak for Jake, but when I hear a comparison of monos to cats, I think the folks with the best (only?) chance are apparent-wind sailors (49ers, Foiling Moths, etc.). As Garda mentioned, it's not so much about boat handling, but IMHO is all about race strategy and tactics.
EDIT: I'm certainly NOT saying that smart monohull sailors can't learn this, it just takes a long time. How long depends on a lot of factors, but I'd measure it in cycles rather than months or even years.